Background: Duodenitis is an inflammatory condition of the duodenal mucosa. It can be associated with abdominal pain Like peptic ulcer. The present study aim is to evaluate the role of endoscopically confirmed duodenitis not associated with peptic ulcer in the pathogenesis of upper abdominal pain.

Materials and Methods: This study  was conducted in the Department of General Surgery, SUT Medical College, Kerala during the period of Feb 2014-Jan 2015. Total 50 patients were included in the study based on inclusion and exclusion criteria. The patients were explained the procedure and informed consent was obtained. Both sexes were included in the study. All the subjects demographic data was collected; they were evaluated endoscopically for the duodenitis. The data was expressed in number and percentage.

Results: 50 patients were included in the study. 46 were males and 4 were females with age group between 16-60 years. 49 patients had abdominal pain. 26 patients had frequent pain. Maximum patients had moderate pain (23). 15 had Grade-I pain, 23 had Grade-II pain and 8 had GradeIII pain. In the correlation only seven paints showed endoscopic changes with pain.

Conclusion: A significant number of patients showed different grades for abdominal pain in this study. From the study results it can be concluded that duodenitis is a etiological factor for upper abdominal pain not associated with peptic ulcer. There is a requirement of further studies to evaluate the duodenitis with the use of endoscopy for better diagnosis of abdominal pain without peptic ulcer.