Application of skin graft to cover the raw area is on of the commonest procedure done in plastic surgery. Skin graft can be either split thickness or full thickness, depending amount of dermis harvested. Donor site is always a concern for the patient as well surgeon. Hence it is chosen from hidden areas. Donor site complications are sometimes more cumbersome for the patient. As it is surgically created raw area hence every attempt should be taken to provide good healing without any complications. A successful skin graft surgery not only involves good take of the graft but also well healed donor site. Various techniques have been described for optimizing the donor site healing. Autologous Platelet Rich Plasma (APRP) and collagen dressing are popular methods. But comparative studies are not done to prioritize a single modality. Through this paper we would like to highlight the comparison between APRP and collagen dressing in improving donor site healing.