Abstract Human immunodeficiency virus(HIV) and the acquired immunodeficiency syndrome (AIDS) has a profound effect on practice of medicine in 20 years since its discovery. Initially a disease of homosexuals and haemopheliacs,now it affects individuals of every age, sex and socioeconomic group, becoming a worldwide epidemic and spreading into regions of globes such as SE asia.In 2008, there were about 4.7million [3.8million- 5.5million] Asians living with HIV/AIDS including 3,50,000 [2,60,000-4,00,000] who became newly infected in 2007, also about 21,000 children were newly infected with HIV. Head and neck manifestations of disease are prevalent, and upto 100% of HIV patients will have some head and neck presentation of the disease during the course of their illness.Often an Otolaryngologist is the primary physician to diagnose HIV infection. They represent a diverse spectrum of diseases ranging from common complaints treated as sinusitis and otitis media to unique presentations.