Medically inappropriate, ineffective and noneconomical use of pharmaceutical products is commonly observed in the health care system throughout the world and especially so in developing counties. Inappropriate prescription increases the cost of medical treatment and increases morbidity and mortality. The rational use of drugs requires the patients to receive medicines appropriate to their clinical needs, in doses that meet their own individual requirements, for an adequate period of time and at the lowest cost. Rational prescribing forms the corner stone of successful implementation of the rational use of drugs. There is an urgent need to ensure that patients are always given evidence-based, cost-effective and rational treatments. Children constitute about 40% of the Indian populations . One significant study has shown that potentially harmful medication error can be three times more common in paediatric population than in adults. Therefore the present study was planned to understand the prescription pattern of paediatric patients in the Yavatmal District, India.