Introduction: Worldwide, nodular goitre remains a problem of enormous magnitude affecting no less than 5% of the population. Neither a well formulated nor a simple procedure is available for the management of MNG. Methodology: A total number of 30 were investigated. The investigations included Hemoglobin, total count, differential count,  urine analysis, blood sugar estimation, blood urea estimation, blood grouping and Rh typing, serum cholesterol, X-ray of the neck-AP and lateral views and chest X-ray and ENT examination. Thyroid profile, USG neck and FNAC was  done in all the patients. Results: FNAC was found to be very useful in evaluation of MNG. FNAC was done in all cases and results were compared. This shows that FNAC is 100 % accurate, indispensable tool and is minimally invasive technique. Conclusion: FNAC is indispensable, minimally invasive technique, cost effective, highly accurate technique in diagnosis and management of MNG.