Introduction: Accuracy rates in diagnosis of appendicitis are variable; the role of blood tests, radiological investigations, laparoscopy and computer analysis has been studied. Even with all investigations, the negative appendicectomy rate is 15-30%. Methodology: The source of data for this study was patients admitted to various surgical units in Department of Surgery, K.R. Hospital, which is attached to Mysore Medical College and Research institute. A period of four months has been given for follow up period to study the outcome of Surgery. These patients were diagnosed to have acute appendicitis and were operated on the same day.During the study period, 100 cases with provisional diagnosis of acute appendicitis which were posted for surgery were selected using randomization. Results: In this study, all 100 patients underwent emergency open appendectomy. Conclusion: Negative appendectomy rate can be decreased if appendectomy is avoided in patients where WBC count, neutrophil count and abdominal graded compression USG is normal.