Dermatoglyphics have been correlated with different diseases by many of the studies. Several studies have explored the relationship of dermatoglyphics to schizophrenia, alopecia, mental retardation, congenital heart defects and diabetes melli-tus. Special space is occupied by the ones with the severe congenital and hereditary ocular diseases. There were reports on isolated clinical cases only, or in a small number of patients which demonstrated the presence of important abnormalities or distortions, with clinical implications, in the dermatoglyphic picture of the affected people. However, there is no documented work concerning dermatoglyphics in blind patients of South India.