Advertisement!
Author Information Pack
Editorial Board
Submit article
Special Issue
Editor's selection process
Join as Reviewer/Editor
List of Reviewer
Indexing Information
Most popular articles
Purchase Single Articles
Archive
Free Online Access
Current Issue
Recommend this journal to your library
Advertiser
Accepted Articles
Search Articles
Email Alerts
FAQ
Contact Us
New Indian Journal of Surgery

Volume  3, Issue 3, July - September 2012, Pages 177-177
 

Shortcommunication

Study of CYP17 Gene Polymorphism in Fetal Growth Restriction with Reference to Organochlorine Pesticide Levels

Siddharth Chand, Md. Mustafa, B.D. Banerjee, Kiran Guleria

University College of Medical Sciences and GTB Hospital, Delhi, India

Choose an option to locate / access this Article:
90 days Access
Check if you have access through your login credentials.        PDF      |
|

Open Access: View PDF

DOI:

Abstract

 The cytochrome P-450c17alpha enzyme encoded by the P-450c17alpha (CYP17) gene functions in the key steps of the estrogen synthesis pathway. The genetic variation in the maternal CYP17 gene leads to differences in estrogen level which affects fetal growth and causes fetal growth restriction (FGR). Organochlorine pesticides (OCPs) are endocrine disruptors which alter the normal estrogen-progesterone balance and are reported to be associated with adverse reproductive outcomes.

 


Corresponding Author : Siddharth Chand