Non-operative pathology diagnoses should constitute an essential part of comprehensive work-up of mass lesions. A quick and reliable preliminary diagnosis is essential in the management of such cases as information is valuable for the same day patient counselling and management planning. The possibility of severe complications such as respiratory distress or circulatory compression mandates rapid diagnosis and treatment of lung/mediastinal masses. With an on-site approach, imprint cytology(IC) on core biopsy (CB) can assess the adequacy of biopsy specimens, optimise the biopsy procedure and provide a rapid diagnosis regarding the malignancy or benignity of a lesion. It is an attempt to get the best of both worlds i.e., cytology and histology without significant extra cost. Imprint cytology(IC) on core biopsy (CB) offers an
attempt to get the best of both worlds i.e., cytology and histology without significant extra cost.

Keywords: Imprint cytology; Core biopsy; Mass lesions.