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New Indian Journal of Surgery

Volume  11, Issue 2, April-June 2020, Pages 164-169
 

Original Article

Hormone Receptor Status in Breast Cancer and its Relation to Age and Other Prognostic Factors at Tertiary Care Hospital at Central India

Raju W Gore1, Bharat U Patil2

1Assistant Professor, Department of General Surgery, Shri Vasantrao Naik Government Medical College Yavatmal, Maharashtra 445001, India. 2Associate Professor, Department of Pathology, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, Maharashtra 442102, India.

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DOI: https://dx.doi.org/10.21088/nijs.0976.4747.11220.14

Abstract

 

Introduction: Breast cancer is a major concern in modern India. The growing population of the patients and the increased death toll require immediate attention from the scientific and medical community.
Material and Methods: In this study, we have conducted a rigorous survey between 2012 and 2014 and investigated all possible contexts in relevance to the disease. Detail Analyzis was done for 112 patients.
The focus was made on vital information n such as parity, age during first live birth, complaint details, location and exact clinical features of the problem, association of axillary lymph node, hormone receptor
Analyzis, histopathological grading, and TNM staging. Results: Our study showed that the age of menarche, the presence of lump in a specific quadrant was quite specific and supported the recently reported data. We have found that the mean age of the patient has declined as discussed in some of the recent studies. Only 8% of the participant patients were found to be nulliparous. Very less number of patients (11.60%) were found to link with the disease hereditarily. We observed that presence of positive nodes were almost triple than the patients with negative lymph nodes, thus, chances of survival in those patients
were comparatively lower. Statistical co-relation was found between ER status, PR status, lymph nodes and age of the patients. Conclusion: We expect this study will increase the present understanding of breast cancer in India. Detail Analyzis with larger population may yield
confirmation to our Analyzis.
Keywords: Hormone receptor; ER status; PR status.


Corresponding Author : Bharat U Patil