Context: Perforation of the duodenal ulcer is common emergency surgical with significant morbidity and mortality rates. Operative management either open or lap is the treatment. Several factors determine the morbidity and mortality which were studied in this study. Aims: To study clinical risk factors, sociodemographic factors, in relation to outcome of surgery for duodenal ulcer perforation and analyze the mortality and morbidity in patients with peritonitis due to duodenal ulcer perforation. Materials and Methods: Patients of duodenal ulcer perforation admitted in SVRRGGH between August 2016 to September 2017 were studied prospectively. History, clinical examination, investigations, intraoperative findings and postoperative status, relationship of clinical and socio-demographic factors on peritonitis were documented in proforma. Statistical analysis used: SPSS 11. Results: The most common age group is 60–70 years. Male to female ratio of 7:1. Highest incidence occured during the months of September and October. Common precipitating factors were smoking, alcohol, NSAIDS. Among 110 patients 12 presented in shock, with mortality of 66%. Delayed presentation > 24 hours, Size of perforation > 1 cm, peritoneal contamination > litre were associated with increased mortality. Common postop complications were wound infection, Pneumonia. Mortality is more in elderly age group that is in patients more than 60 years of age. Conclusions: Smoking, alcohol and NSAIDS usage are predisposing factors for duodenal ulcer perforation. Early presentation, prompt diagnosis, adequate resuscitation, emergency surgery and postoperative monitoring are useful for successful management and good outcome of perforated peptic ulcer.

Keywords: Duodenal perforation; Peritonitis; Cellen Jones technique.