Context: Stroke is one of the major disorders associated with severe morbidity and mortality. Diabetes is associated with occurrence, poor outcome and also chance of recurrence in stroke patients. Aims: The present study was aimed to identify the severity of stroke among diabetics and how it differs from non diabetics and also to evaluate the outcome of acute ischemic stroke among diabetics and non diabetics for a short course of three and six months period. Settings and Design: A prospective observational cross sectional study for one year period was conducted by Neurology department after ethical approval on cases of acute ischemic stroke. Materials and Methods: Cases were divided into diabetics and non diabetics and socio- demographic data, risk factors were noted and severity of the stroke was assessed by using National Institute of Health stroke scale at the time of admission and Grouped into four based on the score. Outcome of the cases was categorized as dependent/ death and independent and placed in two groups based on modified Rankin score (mRS). Follow up of the cases was done for third and sixth month. Analysis was done by Microsoft excel and Probability <0.01 were considered Results: 300 cases of acute ischemic stroke with 198 males, 102 females and 108 (36%) diabetics and 192 non diabetics (64%) were included. 60-69 years was the most common age group (34%), 62.7% were admitted in <24 hours. Majority of the cases were placed in Group 2 and statistical significance was associated with prognosis among diabetics and non-diabetics. The mortality percentage at the end of third and sixth month in the overall study group was 5.3% and 7.04%. Conclusion: To conclude, our study found a signicant association between diabetes and severity of stroke with NIHSS scoring as a tool of predictor in severity. Diabetes increased the risk of severity of stroke and dependent outcome among the acute ischemic stroke patients.

Keywords: Acute Ischemic stroke; Diabetics: Modi ed Rankin score; NIHSS.