Abstract We report a 23 year old female who concomitantly developed Chronic inflammatory polyradiculoneuropathy (CIDP) with Myasthenia gravis (MG). She initially presented with slowly progressing proximal and distal weakness in all four limbs with areflexia and elevated CSF protein. Electrophysiological studies confirmed the diagnosis of CIDP and started on corticosteroids and immunodulators. However, two months into treatment, her condition deterioted and she presented to emergency department with bilateral ptosis, breathing difficulty, dysphagia and no improvement in motor power. High titres of AchR antibodies, presence of ophthalmoplegia along with neostigmine test confirmed the concomitant diagnosis of MG with CIDP. Steroids along with acetylcholinesterase inhibitors were used to treat MG. Coexistence of two autoimmune disorders in the same patient can be a diagnostic labyrinth which can delay diagnosis and treatment.
Keywords: Myasthenia Gravis; Chronic Inflammatory Demyelinating.