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International Journal of Neurology and Neurosurgery

Volume  13, Issue 2, April-June 2021, Pages 11-15
 

Original Article

Interesting Cases of Pituitary Adenoma with Varied Presentations

MD Zaheeruddin Harsoori Mohammed Minhajuddin1, Sivaraman Vigneshwar2, Perumal Jayakumar3, Priya Senthilkumar4, Radhakrishnan Raghavendran5

1,2Post Graduate Resident, 3Senior Resident, 4,5 Professor, Department of Neurosurgery, Institute of Neurosurgery, Rajiv Gandhi Government General Hospital & Madras Medical College, Chennai 600001, India.

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DOI: http://dx.doi.org/10.21088/ijnns.0975.0223.13221.1

Abstract

Pediatric pituitary adenomas (PPAs) are rare neoplasms sometimes with unusualpresentations and varied clinical course. We describe 2 atypical PPAs to highlight the clinical examination, radiological, hormonal and management aspects. A 6-year-old girl presented with bleeding per vagina with difficulty in walking with breast enlargement without visual disturbances. MRI revealed an enlarged anterior pituitary gland showing intense enhancement on contrast of size 11mm x 16mm without invasion of 3rd ventricle or parasellar extension into cavernous sinuswith USG Abdomen and pelvis revealing complex ovarian cyst with reduced TSH levels suggesting Primary Hypothyroidism. Another 30-year-old male presented with blurring of vision in both eyes with bilateral temporal field defects with absence of secondary sexual characters and decreased libido with decreased testosterone levels and MRI Brain showing non diffusion restricting T1 iso T2 hyperintense lesion in sellarsuprasellar region suggestive of Cystic pituitary macroadenoma with haemorrhage,which was managed surgically. Keywords: Adenoma; Medical; Pituitary; Surgery.


Corresponding Author : R. Raghavendran, Professor, Department of Neurosurgery, Institute of Neurosurgery, Rajiv Gandhi Government General Hospital & Madras Medical College, Chennai 600001, India.