Advertisement!
Author Information Pack
Editorial Board
Submit article
Special Issue
Editor's selection process
Join as Reviewer/Editor
List of Reviewer
Indexing Information
Most popular articles
Purchase Single Articles
Archive
Free Online Access
Current Issue
Recommend this journal to your library
Advertiser
Accepted Articles
Search Articles
Email Alerts
FAQ
Contact Us
Indian Journal of Pathology: Research and Practice

Volume  6, Issue 2 (Part-2), APRIL - JUNE 2017, Pages 398-403
 

Original Article

Granulomatous Mastitis: A Masquerading Entity

Punyashetty Kajal B.*, Patil Tejeshwini**, Singh Chitra***

*Associate Professor **Assistant Professor ***Post-graduate, Department of Pathology, Navodaya Medical College Hospital and Research Centre, Raichur, Karnataka.

Choose an option to locate / access this Article:
90 days Access
Check if you have access through your login credentials.        PDF      |
|

Open Access: View PDF

DOI: DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.62(pt-II)17.10

Abstract

Introduction: Granulomatous mastitis (GM) is a rare chronic inflammatory lesion of breast of unknown etiology. This entity clinically and radiologically may simulate carcinoma and presents as palpable breast lump with history of associated pregnancy, lactation or history of oral contraceptive intake. Cytological diagnosis is difficult as microscopic features are non specific and overlaps with other etiologies. Aims/Objectives:To study clinical presentation and cytological features of granulomatous mastitis with histopathological correlation. Methods: Prospective study of 24 cases was done over a period of three years and diagnosed as granulomatous mastitis on FNAC. Clinical data were collected and histopathological correlation was done among 18 cases. Results: Study comprised of 24 cases of granulomatous mastitis with age group ranging from 18 to 48 years (mean age - 33 years). Out of 24 cases, 16 cases had history of taking oral contraceptive pills and 14 were lactating. All the patients presented with breast lump, with abscess in four cases and axillary lymphadenopathy in three cases. Diagnosis of granulomatous mastitis was done on cytology based on the presence of epithelioid cells either in granulomas or scattered along with multinucleated giant cells against background comprising predominantly of neutrophils. Histopathological correlation was done among 18 cases with 100% correlation. Conclusion: Granulomatous mastitis is essentially a diagnosis of exclusion, which can be established by fine needle cytology in majority of cases thereby preventing unnecessary surgeries. matous mastitis diagnosed on cytology with 100% histopathological correlation.

Keywords: Granulomatous; Mastitis; Cytology; Histopathology; Granulomas.


Corresponding Author : Kajal B. Punyashetty