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Indian Journal of Pathology: Research and Practice

Volume  9, Issue 2 (Part-1), May-August 2020, Pages 103-110
 

Original Article

Histopathological Spectrum of Central Nervous System Tumours in a Tertiary Care Centre

Shruti Vimal1, Arpana Dharwadker2, Vidya Vishwanathan3, Neekita Agarwal4

1-3 Associate Professor, 4Resident, Department of Pathology, Dr. DY Patil Medical College, Hospital and Research Centre, Pimpri, Pune, Maharashtra 411018, India.

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DOI: http://dx.doi.org/10.21088/ijprp.2278.148X.9220.18

Abstract

Background: Central nervous system (CNS) tumours comprise a heterogenous group of neoplasms having a wide spectrum. Various factors such as carcinogenic effects of X-rays, chemotherapeutic drugs, electromagnetic radiations, from appliances like microwaves and mobile phones, have contributed to the increasing incidence of these tumours. Their diagnosis and management are well aided by the newer radiological diagnostic techniques and the neurosurgical procedures.
Methods: A prospective study was conducted which included 90 central nervous system tumour biopsies with the relevant clinical and radiological findings. Results: The study revealed mean age of 42 years. The male to female ratio was 1.0:0.95. Out of total 90 cases of CNS tumours in the study, 83 cases (92.22%) were primary tumours and 7 cases (7.77%) were metastatic tumours Among primary CNS tumours, we encountered meningioma (23.33%) as the commonest neoplasm followed by astrocytoma (18.88%), schwannoma (10%) and pituitary adenoma (8.88%). Frontal lobe was found to be the most common site (22.22%) of brain tumours followed by fronto-parietal region (17.77%). Meningiomas showed a female predilection whereas glioblastomas and various other tumours were seen commonly in males. Conclusion: The histopathological study anchors the diagnosis and management of central nervous system tumours.

Keywords: Astrocytoma; Glioblastoma; Meningioma; Pituitary adenoma; Schwannoma; Central nervous system tumours.
 


Corresponding Author : Shruti Vimal