Introduction: Endoscopy is a commonly done procedure among the patients presenting to gastroenterology department. Of the biopsies taken from Upper GI tract, gastric lesions constitute the majority. The present study was undertaken to determine the prevalence of gastric lesions seen on endoscopic biopsies and to estimate the usefulness of these biopsies in patient care. Materials and Methods: The present study consisted of endoscopic biopsies from stomach received over a period of four years from May 2014 to June 2018 at the department of pathology, MNR Medical College, Sangareddy. The biopsies were fixed with 10% buffered formalin, tissue processing and H&E staining (and special stains where necessary) were done before reporting. Results: A total of 260 cases of endoscopic biopsies from stomach were received, among which non-neoplastic lesions were slightly higher than neoplastic lesions, seen affecting male more than female. Maximum cases were in
the 5th decade of life. Epithelial malignancies constituted the majority of neoplastic lesions and were categorized into various histological subtypes. Conclusion: Even though the non-neoplatic lesions were slightly higher, the majority of neoplastic lesions were malignant. Endoscopic biopsy in correlation with imaging carries a benefit of early detection of the malignancy and thus a better outcome.

Keywords: Endoscopic biopsies; Gastric neoplasm; Histopathology.